In a war-torn era， there were two ninja families that were appointed to responsible positions by Shogun. One was Mikumo-ryu that controlled spiritual ninja arts as ”spirit guard” and the other Mugen-ryu that controlled poisons of the world as ”poison guard”. However， Mugen-ryu was wiped out by the Shogunate after falling under suspicion that they were anti-Shogunate… And in the present world， Hikaru Mikumo， a girl who has solved many difficult cases commissioned by International Security Apparatus， acts as a female ninja that inherits the blood of Mikumo-ryu. Having requested by an investigator Yosuke， a childhood friend of Hikaru’s， she begins investigation of the case on a serial murder of bacterial weapon developers. She gets to know that Mugen-ryu is pulling strings behind the scenes. In formal Mikumo attire， Hikaru goes into battle but Kaede， a descendant of Mugen， tricks her into defeat. Then Hikaru is subjected to a hellish torture by Kaede， who tries to seize the Mikumo’s book of secrets and settle her ancestors’ grudges. Will Hikaru， who is now poisoned all over the body， be able to find means of survival and save the book of secrets? The action play of the super sexy ninja unfolds!